Fakülteler: Recent submissions
Now showing items 1-20 of 1928
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RB1 gene mutations and genetic spectrum in retinoblastoma cases
(Lippincott Williams and Wilkins, 2024)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
Adsorption and desorption of hydroxychloroquine onto sulphur doped graphene powders as a potential drug for COVID-19
(Springer, 2024)Hydroxychloroquine (HCQ) is a very substantial drug active substance that was approved for emergency use by the FDA during the peak of the COVID-19 pandemic due to its potent antiviral properties. In this study, adsorption ... -
Development of sinter linings for high-speed trains
(Walter de Gruyter GmbH, 2024)In this study, brake linings with Cu (copper)-based and Cu-10Sn (bronze)-based matrix structures have been developed and produced by the powder metallurgy method using sinter metal technology for use in high-speed trains. ... -
Clarification of red grape juice by amine-functionalized magnesium silica aerogel
(Elsevier Ltd, 2024)The clarification conditions and the selection of the clarification agent are pivotal in eliminating the haze components from red grape juice (RGJ) while minimizing the loss of functional color components. In this context, ... -
High Expression of miR-218-5p in the Peripheral Blood Stream and Tumor Tissues of Pediatric Patients with Sarcomas
(Springer, 2024)Sarcomas are malignant tumors that may metastasize and the course of the disease is highly aggressive in children and young adults. Because of the rare incidence of sarcomas and the heterogeneity of tumors, there is a need ... -
Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens ( Boiss. & NoE) Grierson using network pharmacology
(WILEY-V C H VERLAG GMBH, 2024)Tanacetum nitens ( Boiss. & No & euml;) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, ... -
Comparison of microRNA expression levels in patients with schizophrenia before and after electroconvulsive therapy
(LIPPINCOTT WILLIAMS & WILKINS, 2024)ObjectiveExploring the role of microRNAs in the antipsychotic efficacy of electroconvulsive therapy (ECT) will contribute to understanding the underlying mechanism through which ECT exerts its therapeutic effects. The ... -
The role of the labor movements in the colonial spaces
(ROUTLEDGE JOURNALS, 2024)This article aims to demonstrate how the working class evolved and was organised in Palestine and Lebanon between 1920 and 1948. Palestine and Lebanon, which share characteristics such as being a part of the Ottoman Empire ... -
The effects of the combination of temozolomide and Eribulin on T98G human glioblastoma cell line
(TAYLOR & FRANCIS INC, 2024)Glioblastoma tumors are the most aggressive primary brain tumors that develop resistance to temozolomide (TMZ). Eribulin (ERB) exhibits a unique mechanism of action by inhibiting microtubule dynamics during the G2/M cell ... -
Exploring Chemical Composition, Antioxidant, Enzyme Inhibitory and Cytotoxic Properties of Glaucium acutidentatum Hausskn. & Bornm. from Turkey Flora
(MDPI, 2024)The present study was performed to determine the chemical constituents, cytotoxicity, antioxidant and enzyme inhibition activities of the aerial parts of Glaucium acutidentatum Hausskn. and Bornm. (family Papaveraceae). ... -
Genetic Alterations in Lung Cancer
(KARE PUBL, 2024)Lung cancer is the leading cause of cancer -related deaths worldwide. Due to the prevalence of late -stage diagnoses, treatment options are frequently constrained. Molecular profiling of lung cancer is crucial for the ... -
Factors associated with psychological distress during genetic counseling in high-risk women with breast cancer in Turkey
(Springer Science and Business Media Deutschland GmbH, 2024)Purpose This study aims to shed light on the rather neglected area of research of psychological distress in women facing genetic counselling in Turkey, where few institutions providing such counselling exist. Methods 105 ... -
COVID-19 Phobia in Pregnant Women and its Effect on Vaccination Attitude Gebelerde COVID-19 Fobisi ve Aşı Tutumuna Etkisi
(GALENOS PUBL HOUSE, 2024)Objective: Coronavirus disease -2019 (COVID-19) vaccination rates among pregnant women are lower than the general population. This study aimed to determine the impact of COVID-19 phobia and vaccination attitudes among ... -
The Relationship between Frontal QRS-T Angle and Vitamin D Deficiency
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Background and Objectives: A deficiency in serum 25-hydroxyvitamin D levels is associated with a number of cardiovascular situations, such as high blood pressure, heart failure, atherosclerotic heart disease, and peripheral ... -
Biological, computational evaluation of novel benzofuranyl derivatives as acetylcholinesterase and butyrylcholinesterase
(Taylor and Francis Ltd., 2024)Aim: A highly efficient one-step method has been developed for the synthesis of benzofuranyl derivatives from 2-benzoylcyclohexane-1-carboxylic acid derivatives using chlorosulfonyl isocyanate. This novel method provides ... -
Unveiling the potential antibacterial mechanism of Melaleuca cajuputi leaf extract by cell morphology studies and molecular docking analysis
(Springer, 2024)The antimicrobial properties of the Melaleuca cajuputi plant have been documented. However, the underlying antimicrobial mechanisms remain relatively unexplored. Thus, this study aimed to investigate the antibacterial ... -
High antibiotic resistance rates in Helicobacter pylori strains in Turkey over 20 years
(Lippincott Williams and Wilkins, 2024)Objective Helicobacter pylori (Hp) eradication therapy is crucial for preventing the development of gastritis, peptic ulcers, and gastric cancer. An increase in resistance against antibiotics used in the eradication of Hp ... -
The Moderating Effect of the Business Group Affiliation on the Relationship between Debt and Earnings Management
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Earnings quality is crucial to provide investors and lenders with accurate information about the economic health of the firm and to help them make the right decisions. This paper examines whether the pooling of financial ... -
Digital natives of the labor market
(Frontiers Media SA, 2024)Introduction Today's labor market is comprised of different generations and in the near future, the majority of it will consist of Generation Z. In this respect, it is of great importance to know the perspective of Generation ... -
The Derivation of Vertical Damping Reduction Factors for the Design and Analysis of Structures Using Acceleration, Velocity, and Displacement Spectra
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Damping reduction factors (DRFs) play a vital role in the seismic design of structures. DRFs have been widely studied due to their primary importance to the lateral resistance of structures subjected to earthquakes. On the ...