ORCID "0000-0002-7511-3355" Fakülteler için listeleme
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Comparison of Crosslinker Types and Initiation Systems of Thermoresponsive PNIPAM Hydrogels
Hatır, Pınar Çakır; Capan, Özlem Yalçın (Düzce Üniversitesi Fen Bilimleri Enstitüsü, 2019)Thermoresponsive hydrogels are three-dimensional polymer networks which undergo conformational changes in aqueous media depending on the external temperature. As the lower critical temperature (LCST) is close to the body ... -
Exome data of developmental and epileptic encephalopathy patients reveals de novo and inherited pathologic variants in epilepsy-associated genes
Capan, Ozlem Yalcin; Yapici, Zuhal; Ozbil, Mehmet; Caglayan, Hande S. (W.B. Saunders Ltd, 2024)Purpose: In Developmental and Epileptic Encephalopathies (DEEs), identifying the precise genetic factors guides the clinicians to apply the most appropriate treatment for the patient. Due to high locus heterogeneity, WES ... -
HNF1A-MODY Mutations in Nuclear Localization Signal Impair HNF1A-Import Receptor KPNA6 Interactions
Fareed, Fareed M. A.; Korulu, Şirin; Özbil, Mehmet; Çapan Yalçın, Özlem (Springer, 2021)Mutations in hepatocyte nuclear factor (HNF)1A gene cause the most common form of Maturity-onset diabetes of the young (MODY), a monogenic subtype of diabetes mellitus. Functional characterization of mutant proteins reveals ... -
De novo 8p23.1 deletion in a patient with absence epilepsy
Akçakaya, Nihan Hande; Çapan Yalçın, Özlem; Schulz, Herbert; Sander, Thomas; Çağlayan, Server Hande; Yapıcı, Zuhal (John Libbey Eurotext, 2017)The 8p23.1 deletion syndrome is a rare multisystem disorder with high penetrance and a variable phenotypic spectrum that includes congenital heart disease (CHD), intellectual disability, behavioural problems, microcephalia, ... -
Synthesis, Characterization and Biocompatibility Oo Plant-Oil Based Hydrogels
Yalçın Çapan, Özlem; Çakır Hatır, Pınar (Trakya University, 2021)Biocompatible hydrogels are used in a variety of biomedical applications, including tissue scaffolds, drug delivery systems, lab/organ-on-a-chips, biosensors, cell-culture studies and contact lenses. The demand for novel ... -
Whole exome sequencing reveals novel candidate gene variants for MODY
Çapan Yalçın, Özlem; Aydın, Neslihan; Yılmaz, Temel; Berber, Ergül (Elsevier, 2020)Maturity-onset diabetes of the young (MODY) is a monogenic subtype of diabetes mellitus. Although 14 genes were associated to different subtypes of MODY, 30-40% of MODY patients have unidentified genetic mutations. In this ...