Yazar "Yazici, Hulya" için listeleme
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Aberrant miR-3135b and miR-1273g-3p expression in the peripheral blood samples of BRCA1/2 (±) ovarian cancer patients
Tuncer, Seref Bugra); Celik, Betul; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Pasin, Ozge; Avsar, Mukaddes; Gultaslar, Busra Kurt; Ghafour, Arash Adamnejad; Uyaroglu, Gamze; Odemis, Demet Akdeniz; Yazici, Hulya (Elsevier Ltd, 2024)Ovarian cancer (OC) ranks as the eighth most prevalent malignancy among women globally. The short non-coding RNA molecules, microRNAs (miRNAs) target multiple mRNAs and regulate the gene expression. Here in this study, we ... -
DNA methylation of KIFC1 gene in determination of histological diagnosis, prognosis and metastasis of lung cancer
Celik, Betul; Pasin, Ozge; Sen, Sena; Tuncer, Seref Bugra; Kayim, Zubeyde Yalniz; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Gultaslar, Busra Kurt; Ghafour, Arash Adamnejad; Yazici, Hulya; Olgac, Necat Vakur (ELSEVIER GMBH, 2023)Background: One of the main features of cancer, especially lung cancer (LC), is abnormal cell division. Abnormal expression of kinesin family member C1 (KIFC1/HSET), which is involved in mitotic cell division and ensures ... -
Factors associated with psychological distress during genetic counseling in high-risk women with breast cancer in Turkey
Anuk, Dilek; Tuncer, Seref Bugra; Ozkan, Mine; Yazici, Hulya (Springer Science and Business Media Deutschland GmbH, 2024)Purpose This study aims to shed light on the rather neglected area of research of psychological distress in women facing genetic counselling in Turkey, where few institutions providing such counselling exist. Methods 105 ... -
Genetic Alterations in Lung Cancer
Bayramova, Jamila; Tarakci, Elif; Huseynova, Gumru; Yazici, Hilal; Yazici, Hulya (KARE PUBL, 2024)Lung cancer is the leading cause of cancer -related deaths worldwide. Due to the prevalence of late -stage diagnoses, treatment options are frequently constrained. Molecular profiling of lung cancer is crucial for the ... -
Genetic Alterations in Lung Cancer
Bayramova, Jamila; Tarakci, Elif; Huseynova, Gumru; Yazici, Hilal; Yazici, Hulya (KARE PUBL, 2024)Lung cancer is the leading cause of cancer -related deaths worldwide. Due to the prevalence of late -stage diagnoses, treatment options are frequently constrained. Molecular profiling of lung cancer is crucial for the ... -
Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing
Tuncer, Seref Bugra; Celik, Betul; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Gultaslar, Busra Kurt; Odemis, Demet Akdeniz; Avsar, Mukaddes; Sen, Fatma; Saip, Pinar Mualla; Yazici, Hulya (Elsevier GmbH, 2024)Hereditary Breast and Ovarian Cancer (HBOC) syndrome is characterized by an increased risk of developing breast cancer (BC) and ovarian cancer (OC) due to inherited genetic mutations. Understanding the genetic variants ... -
High Expression of miR-218-5p in the Peripheral Blood Stream and Tumor Tissues of Pediatric Patients with Sarcomas
Ozdenoglu, Fazilet Yildiz; Odemis, Demet Akdeniz; Erciyas, Seda Kilic; Tuncer, Seref Bugra; Gultaslar, Busra Kurt; Salduz, Ahmet; Buyukkapu, Sema; Olgac, Necat Vakur; Kebudi, Rejin; Yazici, Hulya (Springer, 2024)Sarcomas are malignant tumors that may metastasize and the course of the disease is highly aggressive in children and young adults. Because of the rare incidence of sarcomas and the heterogeneity of tumors, there is a need ... -
Identification of candidate genes in a family with cancer overload by whole-exome sequencing
Odemis, Demet Akdeniz; Kebudi, Rejin; Hassani, Masoumeh; Celik, Betul; Tuncer, Seref Bugra; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Bay, Sema Buyukkapu; Yazici, Hulya (Turkish National Pediatric Society, 2022)Background. Approximately 120 out of every 1 million children in the world develop cancer each year. In Turkey, 2500-3000 children are diagnosed with new cancer each year. The causes of childhood cancer have been studied ... -
Investigation of the methylation changes in the promoter region of RB1 gene in retinoblastoma
Erdogan, Ozge Sukruoglu; Odemis, Demet Akdeniz; Kayim, Zubeyde Yalniz; Gurbuz, Orkun; Tuncer, Seref Bugra; Kilic, Seda; Celik, Betul; Tuncer, Samuray; Bay, Sema Buyukkapu; Kebudi, Rejin; Yazici, Hulya (Elsevier GmbH, 2024)Retinoblastoma is an infrequent neoplasm that arises during childhood from retinal nerve cells and is attributed to the biallelic inactivation of the RB1 gene. In conjunction with anatomical anomalies, it is widely ... -
miR-3653-3p Expression in PBMCs: Unveiling the Diagnostic Potential for Ovarian Cancer
Delek, Fatma Seher Pektopal; Tuncer, Seref Bugra; Odemis, Demet Akdeniz; Erciyas, Seda Kilic; Erdogan, ozge Sukruoglu; Saip, Pinar; Yazici, Hulya (Springer, 2024)Ovarian cancer is typically diagnosed at an advanced stage, recurs early and often, and currently lacks effective treatment. Therefore, overall survival and progression-free survival are relatively short for this disease. ... -
Prenatal Parental Emotion Regulation Difficulties and Infants' Communication Skills
Ada, Figen Eroglu; Sendil, Telat Gul; uncer, Seref Bugra; Yazici, Hulya (HOGREFE AG-HOGREFE AG SUISSE, 2023)Konferans öğesi -
RB1 gene mutations and genetic spectrum in retinoblastoma cases
Odemis, Demet Akdeniz; Kebudi, Rejin; Bayramova, Jamila; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref Bugra; Erdogan, Ozge Sukruoglu; Celik, Betul; Gultaslar, Busra Kurt; Bay, Sema Buyukkapu; Tuncer, Samuray; Yazici, Hulya (LIPPINCOTT WILLIAMS & WILKINS, 2023)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
RB1 gene mutations and genetic spectrum in retinoblastoma cases
Odemis, Demet Akdeniz; Kebudi, Rejin; Bayramova, Jamila; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref Bugra; Erdogan, Ozge Sukruoglu; Celik, Betul; Gultaslar, Busra Kurt; Bay, Sema Buyukkapu; Tuncer, Samuray; Yazici, Hulya (Lippincott Williams and Wilkins, 2024)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
RB1 GENE MUTATIONS IN TURKISH PATIENTS WITH RETINOBLASTOMA
Odemis, Demet Akdeniz; Kebudi, Rejin; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref; Erdogan, Ozge Sukruoglu; Bayramova, Jamila; Celik, Betu; Gultaslar, Busra Kurt; Buyukkapu, Sema Bay; Tuncer, Samuray; Yazici, Hulya (WILEY, 2022)RB1 GENE MUTATIONS IN TURKISH PATIENTS WITH RETINOBLASTOMA -
Thyroid hormone resistance with succinate dehydrogenase-B gene mutation
Erel, Cansu; Cakmak, Ramazan; Ullari, Hulya Hacisahinog; Artan, Selay; Ayse, Kubat Uzum; Aral, Ferihan; TANAKOl, Refik; Yazici, Hulya (Edizioni Minerva Medica, 2022)Resistance to thyroid hormone (RTH) is characterized by non-suppressed TSH concentration despite high T4 and/or T3 levels.1 Resistance may develop at any steps in the hormone receptor binding, signaling, or intracellular ... -
Tuberous Sclerosis Complex and Cancer
Dogan, Tunay; Yazici, Hulya (KARE PUBL, 2023)Tuberous sclerosis complex (TSC) is a neurocutaneous syndrome that can affect multiple organ systems such as the brain, heart, and lung, and neurological disorders such as autism spectrum disorder and mental retardation ...
