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THE EFFECTS OF FACE MASK USE DURING COVID-19 ON SPEECH COMPREHENSION IN GERIATRIC PATIENTS WITH HEARING LOSS WHO USE LIP-READING FOR COMMUNICATION: A PROSPECTIVE CROSS-SECTIONAL STUDY
Sizer, Bilal; Demir, Songul; Yilmaz, Umit; Yeniceli, Nurelis; Budak, Yakup; Yorgancilar, Argun Ediz; Topcu, Ismail (Geriatrics Society, 2022)Objective: Communication difficulties are considered the most significant consequence of hearing loss. This study aimed to determine whether surgical face masks, which have been mandatory throughout the COVID-19 pandemic, ... -
Efficient synthesis and characterization of novel isoxazole derivatives including dihdyropyrazole and methanoisoindole moieties
Gürdere, Meliha Burcu; Ertürk, Fatih; Budak, Yakup; Ceylan, Mustafa (ACG Publications, 2020)Isoxazole and pyrazole derivatives have a wide range of biological activity and they are of great interest to medicinal chemist. In this study, the synthesis and characterization of a series of novel hybrid molecules ... -
Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes inhibition profiles
Koçyiğit, Ümit Muhammet; Budak, Yakup; Gürdere, Meliha Burcu; Erturk, Fatih; Yençilek, Belkız; Taslimi, Parham; Gülçin, İlhami; Ceylan, Mustafa (Taylor & Francis, 2018)The new 1-(4-(3-(aryl)acryloyl)phenyl)-1H-pyrrole-2,5-diones (5a-g) were prepared from 4-aminchalcones (3a-g) and screened for biological activities. All compounds (3a-g and 5a-g), except 3d and 3e displayed good cytotoxic ... -
Synthesis, Antiproliferative and Cytotoxic Activities, DNA Binding Features and Molecular Docking Study of Novel Enamine Derivatives
Gürdere, Meliha Burcu; Aydın, Ali; Yencilek, Belkız; Ertürk, Fatih; Özbek, Oğuz; Erkan, Sultan; Budak, Yakup; Ceylan, Mustafa (WILEY-V C H VERLAG, 2020)Novel enamine derivatives were synthesized from the reaction of lactone and chalcones and their antiproliferative and cytotoxic activities against six cancer cell lines (e. g., HeLa, HT29, A549, MCF7, PC3 and Hep3B) and ...