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Mechanisms of peptide hydrolysis by aspartyl and metalloproteases
(Royal Society of Chemistry, 2016)
Peptide hydrolysis has been involved in a wide range of biological, biotechnological, and industrial applications. In this perspective, the mechanisms of three distinct peptide bond cleaving enzymes, beta secretase (BACE1), ...
Computational insight into the phthalocyanine-DNA binding via docking and molecular dynamics simulations
Phthalocyanines are considered as good DNA binders, which makes them promising anti-tumor drug leads. The purpose of this study is to investigate the interactions between DNA and quaternary metallophthalocyanine derivatives ...