Yazar "Çubuk, Hasan" için Moleküler Biyoloji ve Genetik Bölümü Diğer Yayınlar Koleksiyonu listeleme
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In Silico Analysis of SARS-CoV-2 Spike Protein N501Y and N501T Mutation Effects on Human ACE2 Binding
Çubuk, Hasan; Özbi·l, Mehmet (Elsevier Inc., 2022)The SARS-CoV-2 is an RNA-based virus and the most vital step of its survival is the attachment to hACE2 through its spike protein. Although SARS-CoV-2 has the ability to maintain high accurate replication and it can be ... -
A Review of Functional Characterization of Single Amino Acid Change Mutations in HNF Transcription Factors in MODY Pathogenesis
Çubuk, Hasan; Yalçın Çapan, Özlem (Springer, 2021)Mutations in HNF transcription factor genes cause the most common subtypes of maturity-onset of diabetes of youth (MODY), a monogenic form of diabetes mellitus. Mutations in the HNF1-alpha, HNF4-alpha, and HNF1-beta genes ...